Ankylosing Spondylitis and Chronic Inflammatory Lesions of the Intestines

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Inflammatory Arthropathy – Ankylosing Spondylitis

Introduction Ankylosing spondylitis (AS), also known as Pierre-Marie Strumpell’s disease and, more commonly, as Bechterew’s disease, is nowadays a well-recognized inflammatory disease entity with a prevalence about 0.5%. AS primarily involves the sacroiliac joints (SIJ) and the spine, but also peripheral joints and entheses. The SIJ and spinal involvement cause chronic inflammatory back pain an...

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Urolithiasis in ankylosing spondylitis: Correlation with Bath ankylosing spondylitis disease activity index (BASDAI), Bath ankylosing spondylitis functional index (BASFI) and Bath ankylosing spondylitis metrology index (BASMI)

Background: Increased incidence of renal stone has been reported in ankylosing spondylitis (AS), but unlike some well-known renal involvements, they have not been fully studied. The aim of this study was to investigate the association of AS with urolithiasis and also the relation between urinary stone and severity markers. Methods: One hundred-sixty three AS patients were included in a cross-s...

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Ankylosing spondylitis and inflammatory bowel disease. I. Prevalence of inflammatory bowel disease in patients suffering from ankylosing spondylitis.

To establish the prevalence of inflammatory bowel disease in ankylosing spondylitis (AS), 79 AS patients underwent detailed medical screening, including sigmoidoscopic and roentgenological examination, 48 had gastrointestinal symptoms and the others did not. In 3 patients a diagnosis of Crohn's disease was made which was previously established. In all other patients inflammatory bowel disease c...

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Inflammatory bowel disease in ankylosing spondylitis.

Routine detailed gastroenterological investigations were performed in a series of 47 ankylosing spondylitics. Evidence of chronic inflammatory bowel disease was found in eight patients, a prevalence of 17%. Unsuspected bowel disease was found in the absence of symptoms in three of these patients.

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ASSOCIATION OF HLA-B27 WITH ANKYLOSING SPONDYLITIS IN ISFAHAN, IRAN

Using a standard microcytotoxicity (NIH) technique of tissue typing, the HLA-B27 antigen was identified in 30 out of 34 patients (HH.2%) with classical ankylosing spondylitis (AS), compared to 6 out of 70 controls (H.6%) (P < 0.005). We also found this antigen in 8 out of 76 (10.5%) patients with non-AS arthritis.

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ژورنال

عنوان ژورنال: BMJ

سال: 1957

ISSN: 0959-8138,1468-5833

DOI: 10.1136/bmj.2.5054.1157